We can only speak for ourselves, but our n of few™ testing of this mineral and electrolyte profile showed vast improvements prominently in mood, energy, libido, skin, and stamina. Send us your testimonials!

• Each sachet is meant to be dissolved and viciously stirred in 1 quart (1 liter) of water!
• Avoid using metal anything with it. No big deal, but it's best to prevent metals from leeching.

3 sachets cover your daily adequate intake for nearly all minerals—the exceptions being potassium and magnesium—either due to weight constraints or flavor, or to account for the average diet (e.g. sodium). How many you should take depends on your weight and physical activity level. Personally, we take 2 a day so we're good for a month.

MB-0.1 was formulated to take the elemental amount and the oral bioavailability of each compound into account so that each sachet corresponds to roughly 33% of one's adequate intake for a given mineral.

For Copper and Manganese, It was a manufacturing error. There should have been a leading zero.

For Chromium and others: we take oral bioavailability into account to determine how much to put in our formula. So while It might look like you're getting 1700%DV of elemental Chromium, the oral bioavailability makes that roughly 33.3%.

For the minerals, they correspond to the elemental form! If the magnesium bisglycinate used is 12.5% elemental magnesium and 1,000 mg was used, it would yield 125 mg of magnesium with a specific oral bioavailability. However, chemistry isn't that simple: purity varies, and oftentimes techniques—such as dilution by trituration—have to be employed. This is particularly important when dealing with elements whose clinical effect lies in a narrow band, so the powder amount is scaled up with cellulose to allow precise dosing of the element at the microgram level.

Yes! Spike MB-0.1 was engineered to circumvent these limitations and general antagonism. We will have an article out soon™ on mineral antagonism.

No. For example, zinc induces the production of metallothionein, a protein that preferentially binds to copper in intestinal cells, leading to reduced copper absorption, even if copper transporters are not fully saturated. However, MB-0.1 was formulated with this in mind. For instance, the dose required for the above to come to pass is 50 mg of elemental zinc a day, while 3 sachets of MB-0.1 will put your zinc intake at roughly 18 mg.

The body is a beautifully complex system, so no. Transporters have different affinities for different minerals, meaning the one with the higher affinity will take precedence, and then you have hormones and intracellular feedback which modulate their activity and expression based on your physiological needs for these minerals!

Flexibility! Nature never misses, but the answer to this question is two pronged:

• Depending on your current solar yield, your optimal diet will select for a given substrate: protein and fat, or carbs and fat. Regardless of diet, a healthy liver will produce a sufficient amount of sugar via gluconeogenesis, but for those in high solar yield regions you are free to get it from other, tastier sources.
• Because nature never misses™, it is important to note that sugars in fruit are not "just sugar". An orange for example is 50% sucrose, 25% fructose, and 25% glucose, *embedded within a fiber matrix* composed of both soluble and insoluble fiber which modulate its absorption and gut microbiome activity.

Sodium is the only electrolyte whose absorption is aided by insulin via SGLTs. However, this insulin spike also occurs with stevia as it also spikes insulin, though to a much lesser degree.

Even then a 2023 study showed sugar content beyond 6% by volume impaired sodium rehydration levels, while under 6% only increased them marginally when the quantity of sodium was low.

Year round access to high sugar content foods ain't lindy.

Pharma-grade sodium chloride is synthetically purified and therefore devoid of any microplastics and heavy metals, whereas even very good sea salt will have some. Going this route also allows us to be more precise with the ratios by removing the inherent mineral variability that comes with sea salt.

• For stevia: too much of any compound will cause deleterious effects. MB-0.1 is too low dosage to trigger any negative effects as most of the sweet flavor comes from glycine. But no, you won't become a eunuch/infertile, and the very marginal insulin boost is nullified by insulin sensitizing effects from minerals like chromium.
• For citric acid: some sources are contaminated with mycotoxins. SPIKE analyzes every batch and is transparent about their COAs! Check out our certificate of analysis.

Sure, at… >900 mg a day. At 1-2 mg you can expect:

• Biogenesis via PGA-1a activation
• Higher oxidative stress tolerance and apoptosis regulation via the Nrf2 pathway and GSK-3b inhibition respectively (lower electron leakage)
• Bolstered complex I and IV of the electron transport chain (mitochondrial water go brrr)

More mitochondria, more ATP, lower inflammation.

Lithium rich waters with volcanic origin can have up to 5mg/L!

Chromium picolinate has an oral bioavailability of 1% in humans so this is required for each sachet to cover roughly 17% of your daily needs.